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Using two separate drugs to shed pounds can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you need to err along the side of caution and permit the FDA do its job and demand some study be done in order that the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to generate money and that they would say almost anything to keep people on their own medications. Researchers discovered that participants investing in this drug to get a year, dropped a few pounds within one month and have kept the weight off through the 56 weeks from the study. Contrave is often a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which can be made up of more than one active ingredient, that might make them more effective and safer. Combo-pilling may be the newest fad or even better the newest into the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular is the fact that by right now there are no long term prescription diet pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug can also raise blood pressure level and heartbeat, and really should not be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure level, and also by you are not heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. 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