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Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that creates them prone to benefit from naltrexone, in contrast to about 20% of Caucasians and much less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are still available online ( in the journal Neuropsychopharmacology and will also be published within an upcoming print edition from the journal. Using two separate drugs to lose weight naturally can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it one should err to the side of caution and permit the FDA do its job and demand some research be done in order that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say everything to keep people on their medications. Researchers found out that participants investing in this drug for any year, lost excess weight within one month and have kept the body weight off during the entire 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer. Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular is the fact that as of right now there aren't long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug can also raise hypertension and pulse rate, and mustn't be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. The most common side effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.